More evidence of a genetic basis for autism;
Using DNA samples from 120 families likely to possess a genetic risk factor on chromosome 17, the team found 19 different SERT mutations ( or variants ) in families with multiple affected males, consistent with the well-known sex-bias seen in autism incidence.
Four of these variants were in ‘coding’ regions, or parts of the gene that get translated into protein. The other 15 variants were in ‘noncoding’ regions, which are edited out of the final protein product but may have important regulatory roles in the expression of the gene. “These coding mutations tracked with an increased severity of rigid- compulsive behaviors,” Sutcliffe explained. These types of behaviors are a common characteristic of autism and related disorders like obsessive-compulsive disorders.
The findings underscore the relationship between autism and disorders like OCD and may explain why SSRIs are effective in treating these conditions, he said.
[…]
Based on these findings, Blakely and Sutcliffe predict that there will one day be a way to test autistic children for these gene variants, similar to the testing done for cystic fibrosis, a disease linked to a single gene but triggered by many different mutations.
“Autism has such a high genetic risk, but these new findings suggest that there may be many variants of individual genes at work,” Blakely said.
With such genetic testing, said Sutcliffe, “you might be able to predict which kids would respond positively to particular SSRI medications.”
“We now have concrete evidence in our families that the SERT gene is a risk factor in autism,” Blakely said. “Perhaps more importantly, we also have new pathways that could have some therapeutic end points, and that, to us, is really good news.”
I’m tired of hearing how the medical profession is always trying to blame the patient’s genes for the damage done to VACCINE DAMAGED children!!!
Check out Dr.Catherine Diodatti’s excellent book, (I believe it was from her thesis) about the horrors perpetrated on all children of parents who have never been informed of the presence of MERCURY as preservatives in the vaccines administered to them. You won’t hear the word mercury ( a nerve toxin that attacks the brain) but you will see the name thimersol. The ‘mer’ in that word is from its mercury dirivative.
And watch out, when the government has a wholesale immunization blitz. They are usually clearing out old vaccine before (or just after) it’s shelf life is expired. These lots are the most dangerous!!!
Sincerely Rita Moore
Rita,
You’re wrong. Mercurey is no longer used in vaccines.
Regardless, blaiming a person’s genes for their problems is hardly a visious approach. It’s not like they have control over that.
I agree with you, Rita. The dangers of these vaccinations are well documented.
So… to avoid the one-in-a-million chance that your kid may react to a vaccine, your’re willing to give them even money on, oh, say, polio?
If an anti-vaxer’s kid is damaged for life because they contract something that could have been prevented, or if the kid becomes a carrier and infects others, the parents should face jail time for abusing their own kids and endangering others.
I agree with you too Rita. I’ve met a couple that have an autistic son (now a teenager) and they’ve said a change in behavior was noticed shortly after getting his vaccinations as a baby.
I have a question about vaccinations that I can’t find too much research on..
Why is the MMR vaccine give as such? Why are we giving young babies measles, mumps AND rubella in one shot? It just seems a bit much for a tiny body to take on. Also, can a parent delay vaccinations till the child is a bit older? If I ever breed, this would seem like a logical solution, no?
~B
Remember that tiny body is “taking on” all manner of pathogens every day of his life, as is Mom and Dad. Our world is crawling with viruses and bacteria and vaccines only alert the immune system to their existance so that it’s equipped to recognize them when it’s time to do battle with the real thing.
Blogette wrote —
>> Why is the MMR vaccine give as such? Why are
>> we giving young babies measles, mumps AND
>> rubella in one shot? It just seems a bit
>> much for a tiny body to take on. Also, can
>> a parent delay vaccinations till the child
>> is a bit older? If I ever breed, this would
>> seem like a logical solution, no?
Here’s the recommended vaccination schedule from the Ontario Ministry of Health —
http://www.health.gov.on.ca/english/public/pub/immun/immunization.html
We have two kids — our son is three, our daughter is 7 months.
The vaccinaton schedule is indeed flexible and can be varied. Our son’s schedule was varied for health reasons — he was sick at the times (cold, ear infection — typical kid stuff) he would have received the vaccinations, so they were delayed and given later. He’s had everything that’s on the schedule and we did not notice any adverse effects from the shots — he did not get sick from the shots, he did not have an allergic reaction.
Our daughter has had all of her shots on schedule — she’s not had colds or whatever that would delay the shots (my theory about her not having colds and such so far is that, being a second child, our daughter is living in somewhat less clean environment :o) , which boosts her immune system; she’s been able to breastfeed more effectively than did our son, so she’s getting more of that; she’s also been exposed to more kids earlier in life than our son was; she also gets out more and travels more than did out son very early in life — all, I suspect, likely challenge and strengthen her immune system).
Anyway — the point is: our kids did not get sick with the vaccines. The vaccines do not “give” the kids the disease — they expose the immune system to the genetic material, but they are not intended to give the kid the disease.
The advantage to the MMR seems to be convenience for the parent and less trauma for the kid — it’s a single needle, rather than three needles, one evey 28 or 30 days.
Talk to your pediatrician. Talk to your family doctor. If you feel that your doctor is pressuring you or you don’t feel comfortable with his or her actions or opinions, get a second opinion — take your time.
Blogette wrote —
>> Why is the MMR vaccine give as such? Why are
>> we giving young babies measles, mumps AND
>> rubella in one shot? It just seems a bit
>> much for a tiny body to take on. Also, can
>> a parent delay vaccinations till the child
>> is a bit older? If I ever breed, this would
>> seem like a logical solution, no?
Here’s the recommended vaccination schedule from the Ontario Ministry of Health —
http://www.health.gov.on.ca/english/public/pub/immun/immunization.html
We have two kids — our son is three, our daughter is 7 months.
The vaccinaton schedule is indeed flexible and can be varied. Our son’s schedule was varied for health reasons — he was sick at the times (cold, ear infection — typical kid stuff) he would have received the vaccinations, so they were delayed and given later. He’s had everything that’s on the schedule and we did not notice any adverse effects from the shots — he did not get sick from the shots, he did not have an allergic reaction.
Our daughter has had all of her shots on schedule — she’s not had colds or whatever that would delay the shots (my theory about her not having colds and such so far is that, being a second child, our daughter is living in somewhat less clean environment :o) , which boosts her immune system; she’s been able to breastfeed more effectively than did our son, so she’s getting more of that; she’s also been exposed to more kids earlier in life than our son was; she also gets out more and travels more than did out son very early in life — all, I suspect, likely challenge and strengthen her immune system).
Anyway — the point is: our kids did not get sick with the vaccines. The vaccines do not “give” the kids the disease — they expose the immune system to the genetic material, but they are not intended to give the kid the disease.
The advantage to the MMR seems to be convenience for the parent and less trauma for the kid — it’s a single needle, rather than three needles, one evey 28 or 30 days.
Talk to your pediatrician. Talk to your family doctor. If you feel that your doctor is pressuring you or you don’t feel comfortable with his or her actions or opinions, get a second opinion — take your time.
http://maggiesfarm.anotherdotcom.com/archives/1134-.html
Subways vs. Archeolology, in Instanbul.Preparation, Motivation, Discipline, and Interest – it seems simple to me.�The silliness goes on about women and minorities in math and science. Why doesn’t the National Science Foundation just come out and admit tha
Nuts. Sorry about the double post — machine issues on this end. Kate, please delete as time permits.
So if vaccines cause autism, how do you explain autism and other vaccine related damage in children who have never been vaccinated?
Tignish99, that is a good point. Autism is virtually non-existent in countries that don’t vaccinate.
In countries that don’t vaccinate, the death rate among children is so high that compiling figures on autism is the least of their worries.
A lot of credit has been given to vaccinations that should rightfully have been attributed to basic cleanliness. They discovered germs at about the same time as vaccinations were introduced. Yes, children are dying at a deplorable rate in vaccination-free countries…from filthy living conditions and starvation!
Mrs. Lilly — Polio was a serious problem in Canada until the mid 1950’s. Are you suggesting that Canadians did not discover basic hygiene until the middle of the 20th century? Soap and water did not end polio — the vaccines did.
Vietnam vaccinates 210 million poultry against bird flu
Last Updated Thu, 04 Aug 2005 11:17:15 EDT
CBC News
Is it safe to eat autistic chickens? Would we have to train “special education” chickens so they can help the afflicted ones?
How about we don’t vaccinate them and cross our fingers that a human transmissible form of the bird flu doesn’t wipe out 25% of the earth’s population?
Mrs Lilly I think you misunderstood my post about autism. I was asking how do you explain kids who have autism but are not vaccinated? Also many observe something wrong with a child and automatically point the finger at vaccines. What do these people point their fingers at when the child has something wrong but has not been vaccinated.
“Thanks to the wide-scale administration of OPV to children everywhere, the incidence of polio has been reduced from more than 350,000 annual cases in more than 125 countries in 1988, to under 800 cases at the end of 2003.” http://www.who-nigeria.org/faq#Scene_1
I am sure that saving 349,200 people far outweighs the idea of possible, unproven chance of autism.